The impact of age and receipt antihypertensives to systolic blood pressure and shock index at injury scene and in the emergency department to predict massive transfusion in trauma patients

Table 4 Multivariable logistic regression for predicting massive transfusion stratified by age and antihypertensives

	Aged > 65 years not taking antihypertensives		Aged > 65 years taking antihypertensives		Aged < 65 years not taking antihypertensives		Aged < 65 years taking antihypertensives
	P value	aOR (95% CI)	P value	aOR (95% CI)	P value	aOR (95% CI)	P value	aOR (95% CI)
Male sex	0.613	0.68 (0.16–2.99)	0.593	2.51 (0.09–72.6)	0.997	1.00 (0.29–3.38)	0.108	0.14 (0.01–1.55)
Age, yr	0.836	0.99 (0.88–1.11)	0.271	1.13 (0.91–1.40)	0.039	1.04^* (1.00–1.07)	0.909	0.99 (0.86–1.15)
Prehospital SBP
< 90 mmHg	0.959	1.02 (0.95–2.25)	0.012	94.0^* (4.16–795)	0.237	2.12 (0.61–7.23)	0.441	4.16 (0.11–36.6)
90–110 mmHg	0.290	2.37 (0.48–11.7)	0.024	28.1^* (1.75–52.0)	0.447	1.58 (0.49–5.12)	0.049	10.3^* (1.01–44.7)
> 110 mmHg (reference)	–	1.00	–	1.00	–	1.00	–	1.00
SI > 1.0. ED initial	0.002	10.3^* (2.27–46.3)	0.291	8.04 (0.17–83.8)	0.044	3.87^* (1.36–11.0)	0.802	0.67 (0.03–15.1)
RTS	0.015	0.49^* (0.28–0.87)	0.087	0.35 (0.11–1.16)	0.001	0.59^* (0.43–0.81)	0.147	0.52 (0.22–1.26)
ISS	0.655	1.02 (0.93–1.12)	0.216	1.08 (0.96–1.22)	< 0.001	1.10^* (1.05–1.14)	0.100	1.06 (0.99–1.13)

Adjusted for sex, age, prehospital SBP, SI measured at ED admission, RTS, and ISS
aOR adjusted odds ratio, CI confidence interval, ED emergency department, ISS Injury Severity Score, RTS Revised Trauma Score, SBP systolic blood pressure, SI shock index
*P value < 0.05

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