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|
Outcome: any bleeding
|
OR (95% CI)
|
p
|
|---|
|
Type of anticoagulation
|
|
VKA
|
1.000 base
| |
|
DOAC
|
0.678 (0.498–0.924)
|
0.014
|
|
Age, per year increase
|
1.022 (1.003–1.041)
|
0.022
|
|
Hypertension
|
0.748 (0.553–0.012)
|
0.060
|
|
Cerebrovascular disease
|
0.570 (0.407–0.799)
|
0.001
|
|
Renal insufficiency
|
0.664 (0.489–0.901)
|
0.009
|
|
PAVD
|
0.775 (0.463–1.297)
|
0.332
|
|
Liver insufficiency
|
0.539 (0.158–1.840)
|
0.324
|
|
COPD
|
0.466 (0.263–0.826)
|
0.009
|
|
Malignancy
|
0.864 (0.551–1.356)
|
0.525
|
|
Dementia
|
0.890 (0.581–1.365)
|
0.594
|
|
Alcoholism
|
1.606 (0.598–4.311)
|
0.347
|
|
Peptic ulcer disease
|
1.257 (0.888–1.779)
|
0.197
|
|
No. of medications, per additional drug more
|
1.016 (0.973–1.062)
|
0.470
|
|
No. of diagnosis, per additional diagnosis
|
0.889 (0.803–0.984)
|
0.023
|
- Abbreviation: COPD Chronic obstructive pulmonary disease; DOAC Direct oral anticoagulants, No Number OR Odds ratio, PAVD Peripheral artery disease, VKA Vitamin K antagonist